Best American Restaurants in Depew, NY
We list 19 American restaurants in Depew, NY.
Updated October 2026
Ambience:
Fine Dining
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Denny's
Penora's Pizzeria
Applebee's
Forestview Restaurant
French Pub
John & Mary's Restaurant
Kentucky Greg's Hickory Pit
Mooney's Sports Bar & Grill
Santora's Pizza Cafe
Hillview Restaurant
The Pub
Panera Bread
How many American restaurants are there in Depew, NY?
19 are listed so far. None has five or more diner reviews in our data, so the list isn't ranked by rating yet.