Best American Restaurants in Odessa, TX

We list 41 American restaurants in Odessa, TX.

Updated October 2026

Cuisines: North Indian South Indian Chinese Italian Biryani Pizza Seafood
Ambience: Fine Dining
Clear filter
American Barbecue
4.8
Bottoms Up
4101 E 52nd St, Odessa, TX
American, Caterers
American Bar & Grills
4.8
Big Daddys Grill & Bar
1121 E 42nd St, Odessa, TX
Seafood, Bar & Grills
American Chicken
4.8
Sonic Drive-In
3823 E 52nd St, Odessa, TX
Chicken, Fast
American Hamburgers & Hot Dogs
4.8
Texas Burger
1507 John Ben Shepperd Pkwy, Odessa, TX
Hamburgers & Hot Dogs, American
American Barbecue
4.8
Johnny's Bar B Que
2201 Kermit Hwy, Odessa, TX
Barbecue, Caterers
American Hamburgers & Hot Dogs
The Permian Basin Hamburger Co Downtown
520 N Grant Ave, Odessa, TX
Hamburgers & Hot Dogs, American
American Caterers
Quiznos
500 W 4th St, Odessa, TX
Sandwich Shops, Fast
American Fast
Stars Drive-In
9012 W University Blvd, Odessa, TX
Fast, American
American Fast
Stars Drive In Of Odessa
1015 E 8th St, Odessa, TX
Fast, American
American Fast
Charley's Grilled Subs
3824 E 42nd St, Odessa, TX
American, Fast
American Fast
Charley's Grilled Subs
2131 E 8th St, Odessa, TX
American, Fast
American Fast
Charley's Grilled Subs
2625 N County Rd W, Odessa, TX
American, Fast

How many American restaurants are there in Odessa, TX?

41 are listed so far. None has five or more diner reviews in our data, so the list isn't ranked by rating yet.

Also explore in Odessa, TX

Chinese North Indian