Best American Restaurants in Port Saint Lucie, FL
We list 49 American restaurants in Port Saint Lucie, FL.
Updated October 2026
Ambience:
Fine Dining
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Americana Cafe
Lefty's Wings & Grill
Grandpa's Diner
Joes Fine Hot Dogs
Miller's Ale House - Port St Lucie
The 19th Hole at the Saints
Applebee's
Berry Fresh Cafe
Cheddar's Scratch Kitchen
Chili's Grill & Bar
Culver's
Duffys Sports Grill
How many American restaurants are there in Port Saint Lucie, FL?
49 are listed so far. None has five or more diner reviews in our data, so the list isn't ranked by rating yet.